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Hormones

Serotonin Blood Test Results Explained

Serotonin is a neurotransmitter that may influence mood, sleep, appetite, and digestive function. Often referred to as a "feel-good" chemical, it is primarily produced in the gut and plays a role in overall well-being.

Turnaround up to 72 hours, estimate Turnaround: up to 72 hours after your blood draw (estimate).

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
umol/l
Low 0.28 Normal 1.14 High
Female Your group
umol/l
Low 0.28 Normal 1.14 High

Reference values can vary between laboratories. Discuss your results with your GP for explanation and treatment decisions.

Serotonin: what this test measures

This test measures the level of serotonin in your blood, reported in umol/l. Blood serotonin levels may reflect overall serotonin production, though they do not directly measure brain serotonin activity. Your healthcare provider can provide context.

Serotonin: why this value matters

Serotonin plays a role in regulating mood, sleep cycles, and digestive health. Imbalanced levels may be associated with mood changes, sleep difficulties, or gastrointestinal issues. Discuss your results with your healthcare provider for personalized guidance.

Serotonin: how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Results
Turnaround: up to 72 hours after your blood draw (estimate).
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

Serotonin: when is testing worthwhile?

Testing may be considered when experiencing persistent mood changes, unexplained sleep disturbances, or digestive irregularities. Some healthcare providers may recommend serotonin testing as part of a broader evaluation of neurotransmitter or hormonal function.

Serotonin: symptoms of a high or low value

Low Levels

Some people with low serotonin levels may experience low mood, anxiety, difficulty sleeping, increased appetite for carbohydrates, or irritability. Low serotonin could potentially be associated with reduced feelings of well-being over time.

High Levels

Some people with elevated serotonin levels may experience restlessness, rapid heart rate, diarrhea, or muscle twitching. Significantly elevated levels could potentially indicate serotonin syndrome, which requires immediate medical attention.

Serotonin: lifestyle and this value

Regular physical activity, adequate sunlight exposure, and a balanced diet rich in tryptophan-containing foods may support healthy serotonin levels. Stress management techniques could also be beneficial. Consult your healthcare provider for personalized recommendations.

Serotonin: frequently asked questions

What does a blood serotonin test measure?

A blood serotonin test measures the amount of serotonin circulating in your bloodstream, reported in umol/l. Most blood serotonin is found in platelets. This test may not directly reflect brain serotonin levels, so discuss interpretation with your healthcare provider.

Can diet influence serotonin levels?

Certain foods containing tryptophan, such as turkey, eggs, nuts, and seeds, may support serotonin production. A balanced diet with adequate protein and complex carbohydrates could help maintain healthy levels. Your healthcare provider can offer dietary guidance.

Is serotonin only related to mood?

While serotonin is often associated with mood regulation, it also plays roles in sleep, appetite, digestion, and blood clotting. Approximately 90% of serotonin is produced in the gut, highlighting its broader physiological significance beyond mood.

Tests with related values

These panels measure values from the same category as this marker.

Results without a doctor's assessment

You receive your values with the unit and reference range. A doctor's assessment is not part of this site. Discuss your results with your GP for explanation and treatment decisions.

Serotonin

€65,-