Lupus Anticoagulant Test
Lupus Anticoagulant is an antiphospholipid antibody that paradoxically increases thrombosis risk despite prolonging clotting times in laboratory tests. It is one of the key markers for antiphospholipid syndrome (APS) and is not specific to lupus despite its name.
Turnaround up to 72 hours, estimate Turnaround: up to 72 hours after your blood draw (estimate).
Reference Ranges
Reference values can vary between laboratories. Discuss your results with your GP for explanation and treatment decisions.
Lupus Anticoagulant: what this test measures
This test detects the presence of lupus anticoagulant antibodies through a series of phospholipid-dependent clotting assays. It is reported as positive or negative, not as a quantitative level.
Lupus Anticoagulant: why this value matters
Lupus anticoagulant is the strongest predictor of thrombosis among the antiphospholipid antibodies. Persistent positivity (confirmed at 12+ weeks) is required for APS diagnosis.
Lupus Anticoagulant: how the blood test works
- Referral
- No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
- The draw
- A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
- Results
- Turnaround: up to 72 hours after your blood draw (estimate).
- Where
- 650+ draw sites run by independent laboratories across the Netherlands. Draw sites
Lupus Anticoagulant: when is testing worthwhile?
Testing could be indicated for unexplained thrombosis, recurrent pregnancy loss, unexplained prolonged aPTT, or suspected antiphospholipid syndrome.
Lupus Anticoagulant: symptoms of a high or low value
Low Levels
A negative result means lupus anticoagulant was not detected, which is normal and does not require follow-up.
High Levels
A positive lupus anticoagulant is associated with increased risk of venous and arterial thrombosis, stroke, and pregnancy complications including recurrent miscarriage and pre-eclampsia.
Lupus Anticoagulant: lifestyle and this value
If lupus anticoagulant is persistently positive, discuss long-term anticoagulation with your healthcare provider. Reduce modifiable thrombosis risk factors and avoid oestrogen-containing contraception.
Lupus Anticoagulant: frequently asked questions
Does lupus anticoagulant mean I have lupus?
No. Despite its name, lupus anticoagulant can occur in people without lupus. It is found in antiphospholipid syndrome, other autoimmune conditions, and sometimes in healthy individuals.
Why does it cause clotting if it is called an anticoagulant?
The name is misleading. It prolongs clotting in laboratory tests but promotes clotting in the body. This paradox is a key feature of antiphospholipid antibodies.
How many times must it be positive for diagnosis?
Antiphospholipid syndrome requires persistent positivity confirmed on two occasions at least 12 weeks apart.
Results without a doctor's assessment
You receive your values with the unit and reference range. A doctor's assessment is not part of this site. Discuss your results with your GP for explanation and treatment decisions.
Lupus Anticoagulant
€98,-