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Inflammation

Homocysteine Blood Test

Homocysteine is an amino acid produced during protein metabolism. Elevated levels may be associated with an increased risk of cardiovascular disease, cognitive decline, and other health conditions.

Turnaround up to 72 hours, estimate Turnaround: up to 72 hours after your blood draw (estimate).

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
umol/L
Normal < 15 High
Female Your group
umol/L
Normal < 15 High

Reference values can vary between laboratories. Discuss your results with your GP for explanation and treatment decisions.

Homocysteine: what this test measures

This test measures the level of homocysteine in your blood. It is influenced by vitamin B12, folate, and vitamin B6 status, which are needed to metabolise homocysteine.

Homocysteine: why this value matters

Elevated homocysteine may be associated with cardiovascular disease, blood clots, and cognitive decline. It can also indicate B-vitamin deficiencies. Consult your healthcare provider for personalised guidance.

Homocysteine: how the blood test works

Referral
No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw
A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Results
Turnaround: up to 72 hours after your blood draw (estimate).
Where
650+ draw sites run by independent laboratories across the Netherlands. Draw sites

Homocysteine: how to prepare

  1. Preferably fasting

    Recommended

    Coming fasting gives a slightly cleaner value, but it is not required. If it suits you, eat nothing from 22:00 the evening before and drink only water.

  • Water is always fine. Drink as usual beforehand, it makes the draw easier.
  • Take your usual medication, unless your own doctor told you otherwise.

Homocysteine: when is testing worthwhile?

Testing may be recommended if you have a family history of cardiovascular disease, unexplained blood clots, or symptoms of B-vitamin deficiency.

Homocysteine: symptoms of a high or low value

Low Levels

Low homocysteine levels are generally considered favourable and are not associated with health concerns.

High Levels

High homocysteine itself may not cause noticeable symptoms but is associated with increased risk of cardiovascular events, blood clots, and cognitive issues over time.

Homocysteine: what to do about an abnormal value

Male

If Low

Low homocysteine is favourable and indicates low cardiovascular risk.

If High

Elevated homocysteine increases cardiovascular risk. Consider B vitamins (B12, B6, folate).

Female

If Low

Low homocysteine is favourable and indicates low cardiovascular risk.

If High

Elevated homocysteine increases cardiovascular risk. Consider B vitamins (B12, B6, folate).

Homocysteine: lifestyle and this value

Ensure adequate intake of folate, vitamin B12, and vitamin B6 through foods such as leafy greens, legumes, eggs, and fortified cereals. Limiting alcohol and maintaining a balanced diet may help manage homocysteine levels.

Homocysteine: frequently asked questions

How can I lower my homocysteine?

Adequate intake of folate, B12, and B6 may help lower homocysteine. Discuss supplementation and dietary changes with your healthcare provider.

Is homocysteine a reliable heart disease marker?

Elevated homocysteine is considered an independent risk factor, though it is best evaluated alongside other cardiovascular markers. Consult your healthcare provider.

Can genetics affect homocysteine levels?

Yes, certain genetic variations (such as MTHFR) can affect how your body processes homocysteine. Your healthcare provider can advise on testing and management.

Tests with related values

These panels measure values from the same category as this marker.

Turnaround 48 hours, estimate

Full blood test

Twenty values from one draw: liver, kidneys, lipids, glucose, blood count, thyroid, iron and inflammation.

ALT (Alanine Aminotransferase) AST (Aspartate Aminotransferase) ALP (Alkaline Phosphatase) GGT (Gamma-Glutamyl Transferase) Creatinine eGFR (Estimated Glomerular Filtration Rate) Total Cholesterol HDL Cholesterol LDL Cholesterol Triglycerides Glucose (Fasting) Hemoglobin Hematocrit Erythrocytes (RBC) Leukocytes (WBC) MCV (Mean Corpuscular Volume) Platelets (Thrombocytes) TSH (Thyroid Stimulating Hormone) Ferritin CRP (C-Reactive Protein)
€199,-

Results without a doctor's assessment

You receive your values with the unit and reference range. A doctor's assessment is not part of this site. Discuss your results with your GP for explanation and treatment decisions.

Homocysteine

€130,-